Director Clinical Pharmacology & DMPK

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. Alumis is seeking a Director of Clinical Pharmacology & DMPK to drive clinical pharmacology strategy and PK/PD modeling for our small-molecule programs in immune-mediated diseases. This role partners closely with cross-functional teams and reports to the Head of Clinical Pharmacology & DMPK. Specific responsibilities include but are not limited to: Lead clinical pharmacology strategy, dose selection, and PK/PD and biomarker planning across early and late-stage programs. Conduct and interpret PK, PK/PD, exposure–response, and simulation analyses using tools such as NONMEM, WinNonlin, R, Python, and S